InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hsp90aa1

Summary

InnateDB Protein

IDBP-542904.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hsp90aa1

Protein Name

heat shock protein 90, alpha (cytosolic), class A member 1

Synonyms

86kDa; 89kDa; AL024080; AL024147; hsp4; Hsp86-1; Hsp89; Hsp90; Hspca;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121138

InnateDB Gene

IDBG-172055 (Hsp90aa1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
They are also associated with 693 interaction(s) predicted by orthology.

Experimentally validated
Total	53 [view]
Protein-Protein	53 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	693 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0030235	nitric-oxide synthase regulator activity
GO:0042803	protein homodimerization activity
GO:0051082	unfolded protein binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006457	protein folding
GO:0006950	response to stress
GO:0045040	protein import into mitochondrial outer membrane
GO:0050790	regulation of catalytic activity
GO:0051131	chaperone-mediated protein complex assembly

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:96250

InterPro

IPR003594 Histidine kinase-like ATPase, ATP-binding domain
IPR020575 Heat shock protein Hsp90, N-terminal

PFAM

PF02518
PF13581

PRINTS

PR00775

PIRSF

SMART

SM00387

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B7ZC49

UniProt Splice Variant

Entrez Gene

15519

UniGene

Mm.474664

RefSeq

MGI ID

MGI Symbol

Hsp90aa1

OMIM

CCDS

HPRD

IMGT

EMBL

AC152827 AL596265

GenPept