InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prpf6

Summary

InnateDB Protein

IDBP-542928.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prpf6

Protein Name

PRP6 pre-mRNA splicing factor 6 homolog (yeast)

Synonyms

1190003A07Rik; 2610031L17Rik; ANT-1; U5-102K;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117711

InnateDB Gene

IDBG-214170 (Prpf6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	63 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0003723	RNA binding
GO:0043021	ribonucleoprotein complex binding
GO:0050681	androgen receptor binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0006403	RNA localization
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005682	U5 snRNP
GO:0046540	U4/U6 x U5 tri-snRNP complex
GO:0071001	U4/U6 snRNP
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

MGI:1922946

InterPro

IPR010491 PRP1 splicing factor, N-terminal

PFAM

PF06424

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B7ZCS1

UniProt Splice Variant

Entrez Gene

68879

UniGene

Mm.418200

RefSeq

MGI ID

MGI Symbol

Prpf6

OMIM

CCDS

HPRD

IMGT

EMBL

AL844529

GenPept