InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cyth3

Summary

InnateDB Protein

IDBP-543015.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cyth3

Protein Name

cytohesin 3

Synonyms

AI648983; ARNO3; CLM3; Grp1; Pscd3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118290

InnateDB Gene

IDBG-207822 (Cyth3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005086	ARF guanyl-nucleotide exchange factor activity
GO:0005515	protein binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

Biological Process

GO:0032012	regulation of ARF protein signal transduction
GO:0043087	regulation of GTPase activity
GO:0045785	positive regulation of cell adhesion
GO:0048193	Golgi vesicle transport
GO:0090162	establishment of epithelial cell polarity

Cellular Component

GO:0001726	ruffle
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

Protein Structure and Domains

PDB ID

MGI:1335107

InterPro

IPR000904 Sec7 domain

PFAM

PF01369

PRINTS

PIRSF

SMART

SM00222

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YXU3

UniProt Splice Variant

Entrez Gene

19159

UniGene

Mm.398925

RefSeq

MGI ID

MGI Symbol

Cyth3

OMIM

CCDS

HPRD

IMGT

EMBL

AC136746 AC163995

GenPept