InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATOX1

Summary

InnateDB Protein

IDBP-54597.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATOX1

Protein Name

ATX1 antioxidant protein 1 homolog (yeast)

Synonyms

ATX1; HAH1;

Species

Homo sapiens

Ensembl Protein

ENSP00000316854

InnateDB Gene

IDBG-54595 (ATOX1)

Protein Structure

UniProt Annotation

Function

Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitous.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005507	copper ion binding
GO:0016530	metallochaperone activity
GO:0016531	copper chaperone activity
GO:0032767	copper-dependent protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006825	copper ion transport
GO:0030001	metal ion transport

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR006121 Heavy metal-associated domain, HMA

PFAM

PF00403

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O00244

PhosphoSite

PhosphoSite-O00244

TrEMBL

E5RGN3

UniProt Splice Variant

Entrez Gene

475

UniGene

Hs.681736

RefSeq

NP_004036

HUGO

HGNC:798

OMIM

602270

CCDS

CCDS47317

HPRD

03779

IMGT

EMBL

AC011374 AC091982 AK293063 AY165037 AY986502 BC112248 BC112250 BT009786 CH471062 U70660

GenPept

AAC51227 AAI12249 AAI12251 AAN84554 AAP88788 AAX81411 BAF85752 EAW61663 EAW61664