Version 5.4
Homo sapiens Protein: TASP1
Summary
InnateDB Protein IDBP-54632.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TASP1
Protein Name taspase, threonine aspartase, 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000338624
InnateDB Gene IDBG-54630 (TASP1)
Protein Structure
UniProt Annotation
Function Protease involved in KMT2A/MLL1 processing and, consequently, in the correct expression of the early HOXA gene cluster. {ECO:0000269PubMed:14636557}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004298 threonine-type endopeptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000246 Peptidase T2, asparaginase 2
IPR029055 Nucleophile aminohydrolases, N-terminal
PFAM PF01112
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H6P5
PhosphoSite PhosphoSite-Q9H6P5
TrEMBL
UniProt Splice Variant
Entrez Gene 55617
UniGene Hs.348297
RefSeq NP_060184
HUGO HGNC:15859
OMIM 608270
CCDS CCDS13116
HPRD 07460
IMGT
EMBL AK000219 AK025671 AL121754 AL121782 BC025266
GenPept AAH25266 BAA91018 BAB15209 CAC01509 CAI21890 CAI22071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca