Version 5.4
Homo sapiens Protein: ELAVL2
Summary
InnateDB Protein IDBP-54763.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELAVL2
Protein Name ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
Synonyms HEL-N1; HELN1; HUB;
Species Homo sapiens
Ensembl Protein ENSP00000223951
InnateDB Gene IDBG-54761 (ELAVL2)
Protein Structure
UniProt Annotation
Function Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.
Subcellular Localization
Disease Associations
Tissue Specificity Brain; neural-specific.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR002343 Paraneoplastic encephalomyelitis antigen
IPR006548 Splicing factor ELAV/HuD
PFAM PF00076
PRINTS PR00961
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q12926
PhosphoSite PhosphoSite-Q12926
TrEMBL C9JB16
UniProt Splice Variant
Entrez Gene 1993
UniGene Hs.166109
RefSeq NP_001164668
HUGO HGNC:3313
OMIM 601673
CCDS CCDS55298
HPRD 03396
IMGT
EMBL AB209294 AL161628 AL445623 BC030692 CH471071 U12431 U29943
GenPept AAA69698 AAA70417 AAH30692 BAD92531 CAC22160 CAI13376 EAW58581 EAW58582

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca