Version 5.4
Homo sapiens Protein: PRDM4
Summary
InnateDB Protein IDBP-55212.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRDM4
Protein Name PR domain containing 4
Synonyms PFM1;
Species Homo sapiens
Ensembl Protein ENSP00000228437
InnateDB Gene IDBG-55210 (PRDM4)
Protein Structure
UniProt Annotation
Function May function as a transcription factor involved in cell differentiation.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in many tissues. Highly expressed in ovary, testis, pancreas, brain, heart and prostate.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007165 signal transduction
GO:0008283 cell proliferation
GO:0032259 methylation
GO:0045786 negative regulation of cell cycle
GO:0048011 neurotrophin TRK receptor signaling pathway
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001214 SET domain
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
IPR017124 PR-domain zinc finger protein PRDM4
PFAM PF00856
PF00096
PRINTS
PIRSF PIRSF037161
SMART SM00317
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKN5
PhosphoSite PhosphoSite-Q9UKN5
TrEMBL F8VRG2
UniProt Splice Variant
Entrez Gene 11108
UniGene Hs.705747
RefSeq NP_036538
HUGO HGNC:9348
OMIM 605780
CCDS CCDS9115
HPRD 10425
IMGT
EMBL AC007622 AF144757 AL133083 BC035581 CH471054
GenPept AAD55249 AAH35581 CAB61401 EAW97804 EAW97805

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca