Version 5.4
Homo sapiens Protein: HUS1B
Summary
InnateDB Protein IDBP-55945.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HUS1B
Protein Name HUS1 checkpoint homolog b (S. pombe)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000370293
InnateDB Gene IDBG-55943 (HUS1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes. {ECO:0000269PubMed:11944979}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000077 DNA damage checkpoint
GO:0006281 DNA repair
Cellular Component
GO:0005730 nucleolus
GO:0030896 checkpoint clamp complex
Protein Structure and Domains
PDB ID
InterPro IPR007150 Checkpoint protein Hus1/Mec3
IPR016580 Cell cycle checkpoint, Hus1
PFAM PF04005
PRINTS
PIRSF PIRSF011312
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NHY5
PhosphoSite PhosphoSite-Q8NHY5
TrEMBL
UniProt Splice Variant
Entrez Gene 135458
UniGene Hs.669039
RefSeq NP_683762
HUGO HGNC:16485
OMIM 609713
CCDS CCDS4470
HPRD 13722
IMGT
EMBL AF508547 AL357054 BC101697 BC101699
GenPept AAI01698 AAI01700 AAM28904 CAI15190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca