InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SERPINB9

Summary

InnateDB Protein

IDBP-56652.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SERPINB9

Protein Name

serpin peptidase inhibitor, clade B (ovalbumin), member 9

Synonyms

CAP-3; CAP3; PI-9; PI9;

Species

Homo sapiens

Ensembl Protein

ENSP00000370074

InnateDB Gene

IDBG-56650 (SERPINB9)

Protein Structure

UniProt Annotation

Function

Granzyme B inhibitor.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	31 [view]
Protein-Protein	31 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Biological Process

GO:0002448	mast cell mediated immunity
GO:0006955	immune response
GO:0010951	negative regulation of endopeptidase activity
GO:0030162	regulation of proteolysis
GO:0043066	negative regulation of apoptotic process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087	innate immune response (InnateDB)
GO:0071391	cellular response to estrogen stimulus