Version 5.4
Homo sapiens Protein: HOXB6
Summary
InnateDB Protein IDBP-56847.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOXB6
Protein Name homeobox B6
Synonyms Hox-2.2; HOX2; HOX2B; HU-2;
Species Homo sapiens
Ensembl Protein ENSP00000225648
InnateDB Gene IDBG-56845 (HOXB6)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR017995 Homeobox protein, antennapedia type
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00025
PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P17509
PhosphoSite PhosphoSite-P17509
TrEMBL
UniProt Splice Variant
Entrez Gene 3216
UniGene Hs.98428
RefSeq NP_061825
HUGO HGNC:5117
OMIM 142961
CCDS CCDS11531
HPRD 00849
IMGT
EMBL AF287967 AJ270993 AK292200 BC014651 CH471109 K02571 M30597 X58431
GenPept AAA36004 AAG31552 AAH14651 BAF84889 CAA41335 CAA41336 CAB65909 EAW94728 EAW94729 EAW94730 EAW94731

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca