InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TET3

Summary

InnateDB Protein

IDBP-56868.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TET3

Protein Name

tet methylcytosine dioxygenase 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000307803

InnateDB Gene

IDBG-56864 (TET3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046872	metal ion binding
GO:0070579	methylcytosine dioxygenase activity

Biological Process

GO:0006493	protein O-linked glycosylation
GO:0044727	DNA demethylation of male pronucleus
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0055114	oxidation-reduction process
GO:0080111	DNA demethylation
GO:0080182	histone H3-K4 trimethylation

Cellular Component

GO:0001940	male pronucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB007861 AC073263 AC110801 AF466365 BC022243

GenPept

AAH22243 AAO33386 AAX93057 BAA23697

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca