InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HOXB9

Summary

InnateDB Protein

IDBP-56985.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOXB9

Protein Name

homeobox B9

Synonyms

HOX-2.5; HOX2; HOX2E;

Species

Homo sapiens

Ensembl Protein

ENSP00000309439

InnateDB Gene

IDBG-56983 (HOXB9)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0009952	anterior/posterior pattern specification
GO:0030879	mammary gland development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048706	embryonic skeletal system development
GO:0060070	canonical Wnt signaling pathway
GO:0060326	cell chemotaxis

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR001356 Homeobox domain
IPR006711 Hox9, N-terminal activation domain
IPR009057 Homeodomain-like
IPR017112 Homeobox protein Hox9
IPR020479 Homeodomain, metazoa

PFAM

PF00046
PF04617

PRINTS

PR00024

PIRSF

PIRSF037109

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References