InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NMT2

Summary

InnateDB Protein

IDBP-57002.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NMT2

Protein Name

N-myristoyltransferase 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000367407

InnateDB Gene

IDBG-57000 (NMT2)

Protein Structure

UniProt Annotation

Function

Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.

Experimentally validated
Total	20 [view]
Protein-Protein	20 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004379	glycylpeptide N-tetradecanoyltransferase activity

Biological Process

GO:0006499	N-terminal protein myristoylation
GO:0007603	phototransduction, visible light
GO:0009249	protein lipoylation
GO:0016032	viral process
GO:0016056	rhodopsin mediated signaling pathway
GO:0019068	virion assembly
GO:0019082	viral protein processing
GO:0022400	regulation of rhodopsin mediated signaling pathway
GO:0075733	intracellular transport of virus

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000903 Myristoyl-CoA:protein N-myristoyltransferase
IPR016181 Acyl-CoA N-acyltransferase
IPR022676 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal
IPR022677 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal

PFAM

PF01233
PF02799

PRINTS

PIRSF

PIRSF015892

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O60551