Homo sapiens Protein: KCNK7
Summary
InnateDB Protein IDBP-57409.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNK7
Protein Name potassium channel, subfamily K, member 7
Synonyms K2p7.1; TWIK3;
Species Homo sapiens
Ensembl Protein ENSP00000344820
InnateDB Gene IDBG-57407 (KCNK7)
Protein Structure
UniProt Annotation
Function Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003092 Two pore domain potassium channel, TASK family
IPR003280 Two pore domain potassium channel
IPR005408 Two pore domain potassium channel, TWIK family
IPR013099 Two pore domain potassium channel domain
PFAM PF07885
PRINTS PR01095
PR01333
PR01586
PIRSF PIRSF038061
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y2U2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 10089
UniGene Hs.175218
RefSeq NP_203133
HUGO HGNC:6282
OMIM 603940
CCDS CCDS31608
HPRD 06804
IMGT
EMBL AF110522 AF110523 AF110524 BC103809 CH471076
GenPept AAD29578 AAD29579 AAD29580 AAI03810 EAW74413