Version 5.4
Homo sapiens Gene: KCNK7
Summary
InnateDB Gene IDBG-57407.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNK7
Gene Name potassium channel, subfamily K, member 7
Synonyms K2p7.1; TWIK3
Species Homo sapiens
Ensembl Gene ENSG00000173338
Encoded Proteins
IDBP-57409
potassium channel, subfamily K, member 7
IDBP-57411
potassium channel, subfamily K, member 7
IDBP-242043
potassium channel, subfamily K, member 7
IDBP-242045
potassium channel, subfamily K, member 7
IDBP-601559
potassium channel, subfamily K, member 7
IDBP-603132
potassium channel, subfamily K, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:65592855-65595996
Strand Reverse strand
Band q13.1
Transcripts
ENST00000340313 ENSP00000344820
ENST00000342202 ENSP00000343923
ENST00000394217 ENSP00000377765
ENST00000394216 ENSP00000377764
ENST00000530380 ENSP00000431950
ENST00000525254 ENSP00000435449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024936
View Gene Order
ENSBTAG00000010802
Not yet available
Pathways
NETPATH
REACTOME
REACT_75897
Tandem pore domain potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_75779
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) pathway
REACT_75908
Potassium Channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.175218
RefSeq NM_005714 NM_033347 NM_033348 NM_033455
HUGO
OMIM
CCDS CCDS31608 CCDS41673 CCDS8106
HPRD 06804
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca