InnateDB Protein
|
IDBP-57411.7
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
KCNK7
|
Protein Name
|
potassium channel, subfamily K, member 7
|
Synonyms
|
K2p7.1; TWIK3;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000343923
|
InnateDB Gene
|
IDBG-57407 (KCNK7)
|
Protein Structure
|
|
Function |
Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.
|
Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0005244
|
voltage-gated ion channel activity
|
GO:0005267
|
potassium channel activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR003280
Two pore domain potassium channel
IPR013099
Two pore domain potassium channel domain
|
PFAM |
PF07885
|
PRINTS |
PR01333
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9Y2U2
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
A0A024R5B0
|
UniProt Splice Variant |
|
Entrez Gene |
10089
|
UniGene |
Hs.175218
|
RefSeq |
|
HUGO |
HGNC:6282
|
OMIM |
603940
|
CCDS |
CCDS8106
|
HPRD |
06804
|
IMGT |
|
EMBL |
AF110522
AF110523
AF110524
BC103809
CH471076
|
GenPept |
AAD29578
AAD29579
AAD29580
AAI03810
EAW74413
EAW74415
EAW74416
|
|
|