Homo sapiens Protein: GIPR
Summary
InnateDB Protein IDBP-57865.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GIPR
Protein Name gastric inhibitory polypeptide receptor
Synonyms PGQTL2;
Species Homo sapiens
Ensembl Protein ENSP00000263281
InnateDB Gene IDBG-57863 (GIPR)
Protein Structure
UniProt Annotation
Function This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000832 GPCR, family 2, secretin-like
IPR001749 GPCR, family 2, gastric inhibitory polypeptide receptor
IPR001879 GPCR, family 2, extracellular hormone receptor domain
IPR017981 GPCR, family 2-like
PFAM PF00002
PF02793
PRINTS PR00249
PR01129
PIRSF
SMART SM00008
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-P48546
TrEMBL
UniProt Splice Variant
Entrez Gene 2696
UniGene Hs.658534
RefSeq
HUGO HGNC:4271
OMIM 137241
CCDS
HPRD 00670
IMGT
EMBL
GenPept