InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NASP

Summary

InnateDB Protein

IDBP-583326.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NASP

Protein Name

nuclear autoantigenic sperm protein (histone-binding)

Synonyms

FLB7527; PRO1999;

Species

Homo sapiens

Ensembl Protein

ENSP00000438871

InnateDB Gene

IDBG-97982 (NASP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	44 [view]
Protein-Protein	41 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0051879	Hsp90 protein binding

Biological Process

GO:0001824	blastocyst development
GO:0006260	DNA replication
GO:0006335	DNA replication-dependent nucleosome assembly
GO:0006336	DNA replication-independent nucleosome assembly
GO:0007049	cell cycle
GO:0008283	cell proliferation
GO:0015031	protein transport
GO:0043486	histone exchange

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR019544 Tetratricopeptide, SHNi-TPR domain
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF10516
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P49321