InnateDB Protein
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IDBP-584127.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RNPC3
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Protein Name
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RNA-binding region (RNP1, RRM) containing 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000432886
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InnateDB Gene
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IDBG-100587 (RNPC3)
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Protein Structure
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Function |
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA. {ECO:0000269PubMed:16096647, ECO:0000269PubMed:19447915}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:14974681}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in pancreas and kidney. Detected at lower levels in heart, brain, placenta, lung, liver, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. {ECO:0000269PubMed:14974681}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
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Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000504
RNA recognition motif domain
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PFAM |
PF00076
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q96LT9
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PhosphoSite |
PhosphoSite-Q96LT9
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TrEMBL |
X6RLP6
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UniProt Splice Variant |
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Entrez Gene |
55599
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UniGene |
Hs.672995
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RefSeq |
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HUGO |
HGNC:18666
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OMIM |
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CCDS |
CCDS781
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HPRD |
15267
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IMGT |
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EMBL |
AB058742
AC095032
AC105272
AK000015
AK057799
AK289844
AL137730
AY099329
BC010697
BK005195
BX322653
CH471097
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GenPept |
AAH10697
AAM45139
BAA90885
BAB47468
BAB71580
BAF82533
CAB70897
CAH72167
CAH72168
DAA05493
EAW72901
EAW72905
EAW72906
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