Version 5.4
Homo sapiens Gene: RNPC3
Summary
InnateDB Gene IDBG-100587.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNPC3
Gene Name RNA-binding region (RNP1, RRM) containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185946
Encoded Proteins
IDBP-387333
RNA-binding region (RNP1, RRM) containing 3
IDBP-593571
RNA-binding region (RNP1, RRM) containing 3
IDBP-595725
RNA-binding region (RNP1, RRM) containing 3
IDBP-584127
RNA-binding region (RNP1, RRM) containing 3
IDBP-590290
RNA-binding region (RNP1, RRM) containing 3
IDBP-594007
RNA-binding region (RNP1, RRM) containing 3
IDBP-586099
RNA-binding region (RNP1, RRM) containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:103525691-103555239
Strand Forward strand
Band p21.1
Transcripts
ENST00000423855 ENSP00000391432
ENST00000524631 ENSP00000437278
ENST00000531883 ENSP00000431344
ENST00000533099 ENSP00000432886
ENST00000527062 ENSP00000436315
ENST00000533834
ENST00000524641 ENSP00000435440
ENST00000525323
ENST00000532117 ENSP00000434721
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005689 U12-type spliceosomal complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027981
View Gene Order
ENSBTAG00000019091
Not yet available
Cross-References
SwissProt Q96LT9
TrEMBL E9PPV2 X6RLP6
UniProt Splice Variant
Entrez Gene 55599
UniGene Hs.672995
RefSeq NM_017619
HUGO HGNC:18666
OMIM
CCDS CCDS781
HPRD 15267
IMGT
EMBL AB058742 AC095032 AC105272 AK000015 AK057799 AK289844 AL137730 AY099329 BC010697 BK005195 BX322653 CH471097
GenPept AAH10697 AAM45139 BAA90885 BAB47468 BAB71580 BAF82533 CAB70897 CAH72167 CAH72168 DAA05493 EAW72901 EAW72905 EAW72906
RNA Seq Atlas 55599

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca