Version 5.4
Homo sapiens Protein: ADK
Summary
InnateDB Protein IDBP-584525.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADK
Protein Name adenosine kinase
Synonyms AK;
Species Homo sapiens
Ensembl Protein ENSP00000438321
InnateDB Gene IDBG-79046 (ADK)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004001 adenosine kinase activity
GO:0005524 ATP binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0016310 phosphorylation
GO:0043101 purine-containing compound salvage
GO:0044209 AMP salvage
GO:0044281 small molecule metabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001805 Adenosine kinase
IPR011611 Carbohydrate kinase PfkB
IPR029056 Ribokinase-like
PFAM PF00294
PRINTS PR00989
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P55263
PhosphoSite PhosphoSite-P55263
TrEMBL Q9HB33
UniProt Splice Variant
Entrez Gene 132
UniGene Hs.656586
RefSeq NP_001189378
HUGO HGNC:257
OMIM 102750
CCDS CCDS55717
HPRD 00039
IMGT
EMBL AC012046 AC022026 AC022540 AC091699 AF283990 AK290633 AK301590 AK302706 AL357037 AL731576 BC003568 CH471083 U33936 U50196 U90338 U90339
GenPept AAA97893 AAB01689 AAB50234 AAB50235 AAG13958 AAH03568 BAF83322 BAH13519 BAH13786 EAW54555 EAW54556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca