Homo sapiens Protein: SCG3
Summary
InnateDB Protein IDBP-584565.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCG3
Protein Name secretogranin III
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000445205
InnateDB Gene IDBG-12183 (SCG3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Secreted. Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts in intragranular conditions (By similarity). Neuroendocrine and endocrine secretory granules. {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain, heart, kidney, liver and skeletal muscle. {ECO:0000269PubMed:12098761}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0002576 platelet degranulation
GO:0007596 blood coagulation
GO:0030168 platelet activation
Cellular Component
GO:0005576 extracellular region
GO:0030658 transport vesicle membrane
GO:0034774 secretory granule lumen
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WXD2
PhosphoSite PhosphoSite-Q8WXD2
TrEMBL H0YKC2
UniProt Splice Variant
Entrez Gene 29106
UniGene Hs.232618
RefSeq NP_001158729
HUGO HGNC:13707
OMIM 611796
CCDS CCDS53947
HPRD 11538
IMGT
EMBL AC020892 AF078851 AF453583 AK075314 AK290175 AK296466 AY359093 BC009511 BC014539 CH471082
GenPept AAD44483 AAH09511 AAH14539 AAL67431 AAQ89451 BAF82864 BAG52108 BAG59111 EAW77426