InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ARFGAP1

Summary

InnateDB Protein

IDBP-584790.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARFGAP1

Protein Name

ADP-ribosylation factor GTPase activating protein 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000443716

InnateDB Gene

IDBG-85926 (ARFGAP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	34 [view]
Protein-Protein	33 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0005515	protein binding
GO:0008060	ARF GTPase activator activity
GO:0008270	zinc ion binding

Biological Process

GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0015031	protein transport
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0032312	regulation of ARF GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0044267	cellular protein metabolic process
GO:0048205	COPI coating of Golgi vesicle
GO:0061024	membrane organization