Homo sapiens Protein: E2F3
Summary
InnateDB Protein IDBP-585517.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol E2F3
Protein Name E2F transcription factor 3
Synonyms E2F-3;
Species Homo sapiens
Ensembl Protein ENSP00000443418
InnateDB Gene IDBG-64143 (E2F3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 64 [view]
Protein-Protein 46 [view]
Protein-DNA 17 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001047 core promoter binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0000085 mitotic G2 phase
GO:0000278 mitotic cell cycle
GO:0006355 regulation of transcription, DNA-templated
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007219 Notch signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR003316 Transcription factor E2F/dimerisation partner (TDP)
PFAM PF02319
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O00716
PhosphoSite PhosphoSite-O00716
TrEMBL Q24JQ3
UniProt Splice Variant
Entrez Gene 1871
UniGene Hs.269408
RefSeq NP_001230005
HUGO HGNC:3115
OMIM 600427
CCDS CCDS58999
HPRD 02693
IMGT
EMBL AF547386 AL132775 AL136303 BC114554 CR749285 D38550 Y10479
GenPept AAI14555 AAN17846 BAA07553 CAA71504 CAC28598 CAH18140 CAI21471