Homo sapiens Protein: CNTN5
Summary
InnateDB Protein IDBP-585798.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNTN5
Protein Name contactin 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000436185
InnateDB Gene IDBG-68747 (CNTN5)
Protein Structure
UniProt Annotation
Function Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain and kidney and at very low level in placenta. Not expressed in other tissues. In brain, it is highly expressed in the occipital lobe, amygdala, cerebral cortex, frontal lobe, thalamus and temporal lobe. Expressed at moderate level in the cerebellum, substantia nigra, putamen, medulla and hippocampus. Weakly expressed in the spinal cord and caudate nucleus. Weakly or not expressed in the corpus callosum. {ECO:0000269PubMed:11013081}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
PFAM PF00041
PF01108
PF07679
PF07686
PF00047
PRINTS
PIRSF
SMART SM00408
SM00409
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94779
PhosphoSite PhosphoSite-O94779
TrEMBL B4DGP0
UniProt Splice Variant
Entrez Gene 53942
UniGene Hs.742241
RefSeq NP_001230199
HUGO HGNC:2175
OMIM 607219
CCDS CCDS53696
HPRD 06241
IMGT
EMBL AB013802 AB013803 AK294692 AP000760 AP000798 AP000923 AP001892 AP001988 AP002378 AP002428 AP002987 AP003126 AP003441 AP003558 AP004249 BC039255 BC130619 BC144185
GenPept AAH39255 AAI30620 AAI44186 BAA36579 BAA36580 BAG57851