InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MARS

Summary

InnateDB Protein

IDBP-585886.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MARS

Protein Name

methionyl-tRNA synthetase

Synonyms

METRS; MRS; MTRNS; SPG70;

Species

Homo sapiens

Ensembl Protein

ENSP00000446168

InnateDB Gene

IDBG-42746 (MARS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.

Experimentally validated
Total	47 [view]
Protein-Protein	45 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004825	methionine-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006431	methionyl-tRNA aminoacylation

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold
IPR014758 Methionyl-tRNA synthetase
IPR015413 Methionyl/Leucyl tRNA synthetase
IPR029038 Methionyl-tRNA synthetase, Zn-domain

PFAM