Version 5.4
Homo sapiens Protein: ALDH1L2
Summary
InnateDB Protein IDBP-586214.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH1L2
Protein Name aldehyde dehydrogenase 1 family, member L2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000447538
InnateDB Gene IDBG-54556 (ALDH1L2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion {ECO:0000269PubMed:20498374}.
Disease Associations
Tissue Specificity Highly expressed in pancreas, heart, brain and skeletal muscle. {ECO:0000269PubMed:20498374}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0016155 formyltetrahydrofolate dehydrogenase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0016742 hydroxymethyl-, formyl- and related transferase activity
Biological Process
GO:0006730 one-carbon metabolic process
GO:0009058 biosynthetic process
GO:0009258 10-formyltetrahydrofolate catabolic process
GO:0032259 methylation
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR002376 Formyl transferase, N-terminal
PFAM PF00551
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SY69
PhosphoSite PhosphoSite-Q3SY69
TrEMBL
UniProt Splice Variant
Entrez Gene 160428
UniGene Hs.605925
RefSeq
HUGO HGNC:26777
OMIM 613584
CCDS
HPRD 18742
IMGT
EMBL AK095827 BC103934 BC103935 CR627287 CR749561
GenPept AAI03935 AAI03936 BAC04634 CAH10368 CAH18358

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca