Version 5.4
Homo sapiens Protein: PHC1
Summary
InnateDB Protein IDBP-586342.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHC1
Protein Name polyhomeotic homolog 1 (Drosophila)
Synonyms EDR1; HPH1; MCPH11; RAE28;
Species Homo sapiens
Ensembl Protein ENSP00000440488
InnateDB Gene IDBG-17468 (PHC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005537 mannose binding
GO:0015578 mannose transmembrane transporter activity
Biological Process
GO:0015761 mannose transport
Cellular Component
GO:0000323 lytic vacuole
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000296 Cation-dependent mannose-6-phosphate receptor
IPR009011 Mannose-6-phosphate receptor binding domain
IPR028927 Mannose-6-phosphate receptor
PFAM PF02157
PRINTS PR00715
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F5H4U1
UniProt Splice Variant
Entrez Gene 4074
UniGene Hs.731517
RefSeq NP_001193953
HUGO HGNC:6752
OMIM 154540
CCDS CCDS73440
HPRD 16009
IMGT
EMBL AC006581
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca