InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TRPC6

Summary

InnateDB Protein

IDBP-586971.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRPC6

Protein Name

transient receptor potential cation channel, subfamily C, member 6

Synonyms

FSGS2; TRP6;

Species

Homo sapiens

Ensembl Protein

ENSP00000435574

InnateDB Gene

IDBG-68841 (TRPC6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005262	calcium channel activity
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0006811	ion transport
GO:0055085	transmembrane transport
GO:0070588	calcium ion transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002110 Ankyrin repeat
IPR002153 Transient receptor potential channel, canonical
IPR005462 Transient receptor potential channel, canonical 6
IPR005821 Ion transport domain
IPR013122 Polycystin cation channel, PKD1/PKD2
IPR013555 Transient receptor ion channel domain
IPR016024 Armadillo-type fold
IPR020683 Ankyrin repeat-containing domain

PFAM