Version 5.4
Homo sapiens Protein: KDM4C
Summary
InnateDB Protein IDBP-587806.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KDM4C
Protein Name lysine (K)-specific demethylase 4C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000445427
InnateDB Gene IDBG-49006 (KDM4C)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0032454 histone demethylase activity (H3-K9 specific)
GO:0050681 androgen receptor binding
GO:0051213 dioxygenase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0008284 positive regulation of cell proliferation
GO:0033169 histone H3-K9 demethylation
GO:0055114 oxidation-reduction process
Cellular Component
GO:0000790 nuclear chromatin
Protein Structure and Domains
PDB ID
InterPro IPR001965 Zinc finger, PHD-type
IPR003347 JmjC domain
IPR003349 Transcription factor jumonji, JmjN
IPR011011 Zinc finger, FYVE/PHD-type
PFAM PF02373
PF08007
PF02375
PRINTS
PIRSF
SMART SM00249
SM00558
SM00545
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H3R0
PhosphoSite PhosphoSite-Q9H3R0
TrEMBL
UniProt Splice Variant
Entrez Gene 23081
UniGene Hs.734829
RefSeq NP_001140167
HUGO HGNC:17071
OMIM 605469
CCDS CCDS55286
HPRD 12016
IMGT
EMBL AB018323 AB037901 AK304032 AK310439 AL137020 AL161443 AL354707 AL445592 AL513412 BC104859 BC104861 BC143571
GenPept AAI04860 AAI04862 AAI43572 BAA34500 BAB16102 BAG64946 CAH73283 CAH73284 CAI16322 CAI16323 CAI39606 CAI39607 CAI39608

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca