Version 5.4
Homo sapiens Protein: PGRMC1
Summary
InnateDB Protein IDBP-588243.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGRMC1
Protein Name progesterone receptor membrane component 1
Synonyms HPR6.6; MPR;
Species Homo sapiens
Ensembl Protein ENSP00000442821
InnateDB Gene IDBG-83589 (PGRMC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 37 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0020037 heme binding
Biological Process
Cellular Component
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001199 Cytochrome b5-like heme/steroid binding domain
PFAM PF00173
PRINTS PR00363
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O00264
PhosphoSite PhosphoSite-O00264
TrEMBL
UniProt Splice Variant
Entrez Gene 10857
UniGene Hs.90061
RefSeq NP_001269550
HUGO HGNC:16090
OMIM 300435
CCDS CCDS65313
HPRD 02338
IMGT
EMBL AC004835 AJ249131 AK293618 BC034238 CH471161 Y12711
GenPept AAH34238 BAH11549 CAA73248 CAB65109 EAW89881

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca