Version 5.4
Homo sapiens Gene: PGRMC1
Summary
InnateDB Gene IDBG-83589.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGRMC1
Gene Name progesterone receptor membrane component 1
Synonyms HPR6.6; MPR
Species Homo sapiens
Ensembl Gene ENSG00000101856
Encoded Proteins
IDBP-83591
progesterone receptor membrane component 1
IDBP-588243
progesterone receptor membrane component 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:119236245-119244466
Strand Forward strand
Band q24
Transcripts
ENST00000217971 ENSP00000217971
ENST00000535419 ENSP00000442821
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 37 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0020037 heme binding
Biological Process
GO:0007411 axon guidance
Cellular Component
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006373
View Gene Order
ENSBTAG00000019552
Not yet available
Cross-References
SwissProt O00264
TrEMBL Q6IB11
UniProt Splice Variant
Entrez Gene 10857
UniGene Hs.701723 Hs.90061
RefSeq NM_001282621 NM_006667
HUGO HGNC:16090
OMIM 300435
CCDS CCDS14576 CCDS65313
HPRD
IMGT
EMBL AC004835 AJ249131 AK293618 AK313956 BC034238 CH471161 CR456993 DQ496104 Y12711
GenPept AAH34238 ABF47093 BAG36672 BAH11549 CAA73248 CAB65109 CAG33274 EAW89879 EAW89881 EAW89882
RNA Seq Atlas 10857

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca