Version 5.4
Homo sapiens Protein: STAT2
Summary
InnateDB Protein IDBP-588316.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STAT2
Protein Name signal transducer and activator of transcription 2, 113kDa
Synonyms ISGF-3; P113; STAT113;
Species Homo sapiens
Ensembl Protein ENSP00000450985
InnateDB Gene IDBG-40906 (STAT2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 79 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 79 [view]
Protein-Protein 45 [view]
Protein-DNA 33 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR013799 STAT transcription factor, protein interaction
PFAM PF02865
PRINTS
PIRSF
SMART SM00964
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V319
UniProt Splice Variant
Entrez Gene 6773
UniGene Hs.530595
RefSeq
HUGO HGNC:11363
OMIM 600556
CCDS
HPRD 02778
IMGT
EMBL AC025574
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca