InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CLTB

Summary

InnateDB Protein

IDBP-58862.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLTB

Protein Name

clathrin, light chain B

Synonyms

LCB;

Species

Homo sapiens

Ensembl Protein

ENSP00000309415

InnateDB Gene

IDBG-58860 (CLTB)

Protein Structure

UniProt Annotation

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.

Subcellular Localization

Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0042277	peptide binding

Biological Process

GO:0006886	intracellular protein transport
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0005802	trans-Golgi network
GO:0005886	plasma membrane
GO:0030118	clathrin coat
GO:0030130	clathrin coat of trans-Golgi network vesicle
GO:0030132	clathrin coat of coated pit
GO:0060170	ciliary membrane