Version 5.4
Homo sapiens Protein: XPA
Summary
InnateDB Protein IDBP-588831.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XPA
Protein Name xeroderma pigmentosum, complementation group A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000433006
InnateDB Gene IDBG-78000 (XPA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 34 [view]
Protein-Protein 33 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003684 damaged DNA binding
Biological Process
GO:0006289 nucleotide-excision repair
Cellular Component
GO:0005634 nucleus
GO:0045171 intercellular bridge
Protein Structure and Domains
PDB ID
InterPro IPR000465 XPA
IPR009061 DNA binding domain, putative
IPR022652 Zinc finger, XPA-type, conserved site
IPR022656 XPA C- terminal
PFAM PF01286
PF05181
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F2Z2T2
UniProt Splice Variant
Entrez Gene 7507
UniGene Hs.654364
RefSeq
HUGO HGNC:12814
OMIM 611153
CCDS
HPRD 02045
IMGT
EMBL AL445531
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca