Version 5.4
Homo sapiens Protein: ACTN1
Summary
InnateDB Protein IDBP-589039.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACTN1
Protein Name actinin, alpha 1
Synonyms BDPLT15;
Species Homo sapiens
Ensembl Protein ENSP00000444422
InnateDB Gene IDBG-10222 (ACTN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 120 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 122 [view]
Protein-Protein 121 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0051017 actin filament bundle assembly
GO:0051764 actin crosslink formation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002017 Spectrin repeat
IPR002048 EF-hand domain
IPR018159 Spectrin/alpha-actinin
PFAM PF00435
PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5ZEZ4
UniProt Splice Variant
Entrez Gene 87
UniGene Hs.653481
RefSeq
HUGO HGNC:163
OMIM 102575
CCDS
HPRD 00020
IMGT
EMBL AJ844628 AL117694
GenPept CAH59747

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca