InnateDB Protein
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IDBP-589273.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CLTA
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Protein Name
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clathrin, light chain A
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Synonyms
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LCA;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000442869
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InnateDB Gene
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IDBG-64915 (CLTA)
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Protein Structure
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Function |
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
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Subcellular Localization |
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
32
[view]
|
Protein-Protein |
31
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006886
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intracellular protein transport
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GO:0006892
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post-Golgi vesicle-mediated transport
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GO:0007173
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epidermal growth factor receptor signaling pathway
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GO:0007411
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axon guidance
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GO:0016192
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vesicle-mediated transport
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GO:0019886
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antigen processing and presentation of exogenous peptide antigen via MHC class II
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GO:0042059
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negative regulation of epidermal growth factor receptor signaling pathway
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GO:0048011
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neurotrophin TRK receptor signaling pathway
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GO:0061024
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membrane organization
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Cellular Component |
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PDB ID |
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InterPro |
IPR000996
Clathrin light chain
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PFAM |
PF01086
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P09496
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PhosphoSite |
PhosphoSite-P09496
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
1211
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UniGene |
Hs.735741
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RefSeq |
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HUGO |
HGNC:2090
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OMIM |
118960
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CCDS |
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HPRD |
00351
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IMGT |
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EMBL |
AK291078
AK295692
AL158830
AL161792
BC009201
BC019287
BT007170
CH471071
DQ270158
M20471
M20472
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GenPept |
AAA51817
AAA59505
AAH09201
AAH19287
AAP35834
ABB76683
BAF83767
BAG58543
CAD13387
CAD13388
EAW58312
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