InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NLRP6

Summary

InnateDB Protein

IDBP-589489.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NLRP6

Protein Name

NLR family, pyrin domain containing 6

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000433617

InnateDB Gene

IDBG-16041 (NLRP6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005000	vasopressin receptor activity
GO:0005524	ATP binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0050727	regulation of inflammatory response

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR004020 DAPIN domain
IPR007111 NACHT nucleoside triphosphatase
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02758

PRINTS

PIRSF

SMART

SM00368

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P59044

PhosphoSite

PhosphoSite-P59044

TrEMBL

UniProt Splice Variant

Entrez Gene

171389

UniGene

Hs.352611

RefSeq

NP_001263629

HUGO

HGNC:22944

OMIM

609650

CCDS

CCDS60680

HPRD

14806

IMGT

EMBL

AC136475 AF479748 AK292668 AY154461

GenPept

AAL87105 AAO18157 BAF85357