InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: P2RX4

Summary

InnateDB Protein

IDBP-590082.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

P2RX4

Protein Name

purinergic receptor P2X, ligand-gated ion channel, 4

Synonyms

P2X4; P2X4R;

Species

Homo sapiens

Ensembl Protein

ENSP00000439386

InnateDB Gene

IDBG-61373 (P2RX4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001614	purinergic nucleotide receptor activity
GO:0005216	ion channel activity
GO:0005524	ATP binding

Biological Process

GO:0006811	ion transport
GO:0034220	ion transmembrane transport
GO:0035590	purinergic nucleotide receptor signaling pathway

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001429 P2X purinoreceptor
IPR003047 P2X4 purinoceptor

PFAM

PF00864

PRINTS

PR01307
PR01311

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-ENSP00000439386

TrEMBL

F5H2S3

UniProt Splice Variant

Entrez Gene

5025

UniGene

Hs.321709

RefSeq

HUGO

HGNC:8535

OMIM

600846

CCDS

HPRD

09017

IMGT

EMBL

AC069209

GenPept