Version 5.4
Homo sapiens Protein: MARS
Summary
InnateDB Protein IDBP-590123.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARS
Protein Name methionyl-tRNA synthetase
Synonyms METRS; MRS; MTRNS; SPG70;
Species Homo sapiens
Ensembl Protein ENSP00000449787
InnateDB Gene IDBG-42746 (MARS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
Experimentally validated
Total 47 [view]
Protein-Protein 45 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000738 WHEP-TRS
IPR009068 S15/NS1, RNA-binding
IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
PFAM PF00458
PRINTS
PIRSF
SMART SM00991
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YIP0
UniProt Splice Variant
Entrez Gene 4141
UniGene Hs.697828
RefSeq
HUGO HGNC:6898
OMIM 156560
CCDS
HPRD 08864
IMGT
EMBL AC022506
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca