InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CDK4

Summary

InnateDB Protein

IDBP-590909.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CDK4

Protein Name

cyclin-dependent kinase 4

Synonyms

CMM3; PSK-J3;

Species

Homo sapiens

Ensembl Protein

ENSP00000449391

InnateDB Gene

IDBG-43642 (CDK4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 169 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	169 [view]
Protein-Protein	163 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468

protein phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR002575 Aminoglycoside phosphotransferase
IPR011009 Protein kinase-like domain

PFAM

PF00069
PF07714
PF01636

PRINTS

PR00109

PIRSF

SMART

SM00220

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt