Version 5.4
Homo sapiens Protein: PBX1
Summary
InnateDB Protein IDBP-591111.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PBX1
Protein Name pre-B-cell leukemia homeobox 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000439943
InnateDB Gene IDBG-104447 (PBX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 63 [view]
Protein-Protein 48 [view]
Protein-DNA 15 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006694 steroid biosynthetic process
GO:0007548 sex differentiation
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR005542 PBX
IPR009057 Homeodomain-like
PFAM PF00046
PF03792
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P40424
PhosphoSite PhosphoSite-P40424
TrEMBL Q68DD6
UniProt Splice Variant
Entrez Gene 5087
UniGene Hs.720898
RefSeq
HUGO HGNC:8632
OMIM 176310
CCDS
HPRD 08889
IMGT
EMBL AF313396 AF313397 AF313398 AF313399 AF313400 AF313401 AF313402 AF313403 AF313404 AK299673 AL357568 AL359255 AL390119 AL391001 BC101578 CH471067 CR749446 M31522 M86546
GenPept AAA36764 AAA60031 AAG30941 AAI01579 BAG61583 CAH18284 CAH73499 CAI14854 CAI14908 EAW90738

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca