Version 5.4
Homo sapiens Protein: PRPSAP2
Summary
InnateDB Protein IDBP-591128.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRPSAP2
Protein Name phosphoribosyl pyrophosphate synthetase-associated protein 2
Synonyms PAP41;
Species Homo sapiens
Ensembl Protein ENSP00000439129
InnateDB Gene IDBG-34360 (PRPSAP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004749 ribose phosphate diphosphokinase activity
GO:0004857 enzyme inhibitor activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009165 nucleotide biosynthetic process
GO:0043086 negative regulation of catalytic activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR005946 Ribose-phosphate diphosphokinase
IPR029057 Phosphoribosyltransferase-like
PFAM PF14572
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60256
PhosphoSite PhosphoSite-O60256
TrEMBL I3L331
UniProt Splice Variant
Entrez Gene 5636
UniGene Hs.632236
RefSeq NP_001230869
HUGO HGNC:9467
OMIM 603762
CCDS CCDS58525
HPRD 04789
IMGT
EMBL AB007851 AC090286 AC107982 AK303911 AK304544 BC101670 BC101672 BC106050 BC143475 CR457082
GenPept AAI01671 AAI01673 AAI06051 AAI43476 BAA25435 BAG64840 BAG65341 CAG33363

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca