InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TPTE2

Summary

InnateDB Protein

IDBP-591194.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TPTE2

Protein Name

transmembrane phosphoinositide 3-phosphatase and tensin homolog 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000432402

InnateDB Gene

IDBG-12255 (TPTE2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0016791	phosphatase activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000340 Dual specificity phosphatase, catalytic domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR029021 Protein-tyrosine phosphatase-like
IPR029023 Tensin phosphatase, lipid phosphatase domain

PFAM

PF00168
PF00102
PF00782

PRINTS

PR00360
PR00700

PIRSF

SMART

SM00239
SM00194

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt