InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP2A2

Summary

InnateDB Protein

IDBP-591596.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP2A2

Protein Name

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

Synonyms

ATP2B; DAR; DD; SERCA2;

Species

Homo sapiens

Ensembl Protein

ENSP00000450407

InnateDB Gene

IDBG-56943 (ATP2A2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	48 [view]
Protein-Protein	48 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005388	calcium-transporting ATPase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008022	protein C-terminus binding
GO:0019899	enzyme binding
GO:0044548	S100 protein binding
GO:0046872	metal ion binding
GO:0086039	calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential

Biological Process

GO:0006810	transport
GO:0006874	cellular calcium ion homeostasis
GO:0007155	cell adhesion
GO:0007596	blood coagulation
GO:0008152	metabolic process
GO:0008544	epidermis development
GO:0010460	positive regulation of heart rate
GO:0034220	ion transmembrane transport
GO:0055085	transmembrane transport
GO:0055119	relaxation of cardiac muscle
GO:0070296	sarcoplasmic reticulum calcium ion transport
GO:0070588	calcium ion transmembrane transport
GO:0086036	regulation of cardiac muscle cell membrane potential

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016529	sarcoplasmic reticulum
GO:0031095	platelet dense tubular network membrane
GO:0033017	sarcoplasmic reticulum membrane
GO:0043231	intracellular membrane-bounded organelle