InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RNGTT

Summary

InnateDB Protein

IDBP-591880.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RNGTT

Protein Name

RNA guanylyltransferase and 5'-phosphatase

Synonyms

CAP1A; hCAP; HCE; HCE1;

Species

Homo sapiens

Ensembl Protein

ENSP00000442609

InnateDB Gene

IDBG-94245 (RNGTT)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	7 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004484	mRNA guanylyltransferase activity
GO:0004651	polynucleotide 5'-phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0016791	phosphatase activity

Biological Process

GO:0006370	7-methylguanosine mRNA capping
GO:0006397	mRNA processing
GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000340 Dual specificity phosphatase, catalytic domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR001339 mRNA capping enzyme
IPR017074 mRNA capping enzyme, bifunctional
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00782
PF01331

PRINTS

PR00700

PIRSF

PIRSF036958

SMART

SM00194

TIGRFAMs

Post-translational Modifications

Modification

Cross-References