Version 5.4
Homo sapiens Gene: RNGTT
Summary
InnateDB Gene IDBG-94245.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNGTT
Gene Name RNA guanylyltransferase and 5'-phosphatase
Synonyms CAP1A; hCAP; HCE; HCE1
Species Homo sapiens
Ensembl Gene ENSG00000111880
Encoded Proteins
IDBP-94247
RNA guanylyltransferase and 5'-phosphatase
IDBP-94251
RNA guanylyltransferase and 5'-phosphatase
IDBP-591880
RNA guanylyltransferase and 5'-phosphatase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:88610266-88963596
Strand Reverse strand
Band q15
Transcripts
ENST00000369485 ENSP00000358497
ENST00000369475 ENSP00000358487
ENST00000538899 ENSP00000442609
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 7 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004484 mRNA guanylyltransferase activity
GO:0004651 polynucleotide 5'-phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005525 GTP binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0008192 RNA guanylyltransferase activity
GO:0016791 phosphatase activity
GO:0050355 triphosphatase activity
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0006470 protein dephosphorylation
GO:0010467 gene expression
GO:0016032 viral process
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0098507 polynucleotide 5' dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028274
View Gene Order
ENSBTAG00000002725
Not yet available
Pathways
NETPATH
REACTOME
REACT_1470
mRNA Capping pathway
REACT_975
RNA Pol II CTD phosphorylation and interaction with CE pathway
REACT_6237
RNA Pol II CTD phosphorylation and interaction with CE pathway
REACT_6233
Transcription of the HIV genome pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 8732
UniGene Hs.601655 Hs.609061
RefSeq NM_001286426 NM_001286428 NM_003800 XM_006715589
HUGO HGNC:10073
OMIM 603512
CCDS CCDS5017
HPRD 04621
IMGT
EMBL
GenPept
RNA Seq Atlas 8732

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca