Version 5.4
Homo sapiens Protein: MYL6B
Summary
InnateDB Protein IDBP-592037.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYL6B
Protein Name myosin, light chain 6B, alkali, smooth muscle and non-muscle
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000446643
InnateDB Gene IDBG-40062 (MYL6B)
Protein Structure
UniProt Annotation
Function Regulatory light chain of myosin. Does not bind calcium.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008307 structural constituent of muscle
Biological Process
GO:0006936 muscle contraction
GO:0007519 skeletal muscle tissue development
GO:0008152 metabolic process
GO:0030049 muscle filament sliding
Cellular Component
GO:0005829 cytosol
GO:0005859 muscle myosin complex
GO:0016459 myosin complex
GO:0016461 unconventional myosin complex
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P14649
PhosphoSite PhosphoSite-P14649
TrEMBL F8VSA2
UniProt Splice Variant
Entrez Gene 140465
UniGene
RefSeq NP_002466
HUGO HGNC:29823
OMIM 609930
CCDS CCDS8905
HPRD 14721
IMGT
EMBL AC034102 BC012425 BC014400 CH471054 M31211 X16434
GenPept AAA36320 AAH12425 AAH14400 CAA34457 EAW96894 EAW96896 EAW96897

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca