Version 5.4
Homo sapiens Protein: CTSB
Summary
InnateDB Protein IDBP-592475.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTSB
Protein Name cathepsin B
Synonyms APPS; CPSB;
Species Homo sapiens
Ensembl Protein ENSP00000433379
InnateDB Gene IDBG-7654 (CTSB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 47 [view]
Protein-Protein 47 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0045087 innate immune response (InnateDB)
GO:0050790 regulation of catalytic activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR012599 Peptidase C1A, propeptide
PFAM PF08127
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PR00
UniProt Splice Variant
Entrez Gene 1508
UniGene Hs.520898
RefSeq
HUGO HGNC:2527
OMIM 116810
CCDS
HPRD 00287
IMGT
EMBL AC025857 AC069185
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca