Version 5.4
Homo sapiens Protein: NOX4
Summary
InnateDB Protein IDBP-592527.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOX4
Protein Name NADPH oxidase 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000436093
InnateDB Gene IDBG-67316 (NOX4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 2 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:0055114 oxidation-reduction process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000778 Cytochrome b245, heavy chain
IPR013112 FAD-binding 8
IPR013121 Ferric reductase, NAD binding
IPR017938 Riboflavin synthase-like beta-barrel
PFAM PF08022
PF08030
PRINTS PR00466
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PR43
UniProt Splice Variant
Entrez Gene 50507
UniGene Hs.591995
RefSeq
HUGO HGNC:7891
OMIM 605261
CCDS
HPRD 09243
IMGT
EMBL AP001815 AP002404 AP003400
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca